Review article: malignancy in adult celiac disease
- Overall, the risk of other gastrointestinal cancers seems to be limited, and stomach cancer does not appear to be detected more frequently in patients with celiac disease, even though endoscopies are commonly performed.
- Colon cancer also appears to be limited in celiac disease, even in patients first diagnosed with celiac disease late in life. As a result, some have suggested untreated celiac disease may be protective against gastrointestinal cancers. This may be because celiac disease can inhibit absorption or promote faster excretion of fat or fat‑soluble agents, as well as certain other substances (carcinogens) that have been implicated in causing colon cancer.
Additional research is needed to determine what, if any, links may exist between treated and untreated celiac disease and certain types of cancer.
Sources:Freeman HJ. Malignancy in adult celiac disease. World J Gastroenterol 2009 April 7; 15(13): 1581-1583. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669940/