Scientific study: increased prevalence of celiac disease in patients with unexplained infertility in the United States: a prospective study
- Nearly 200 patients with fertility problems were screened for celiac disease, and the rate of occurrence was compared to that of a general population of women in the same age range.
- Results suggested that overall, there was no increase in the occurrence of celiac disease between the women in the study and a general population; the rate of occurrence in this study was 2.1% compared to 1.3% in the general population.
- In a sub-group of 51 women with unexplained infertility, the rate of celiac disease was found to be 5.9%. Based on this finding, the study authors concluded, “Our findings suggest the importance of screening infertile female patients, particularly those with unexplained infertility, for celiac disease.”
Celiac disease may be an important risk factor in women with unexplained infertility. Because it can be managed with gluten-free diets, broader screening may allow interventions to improve fertility issues. More research is needed to confirm this association and assess the effects of dietary intervention on fertility and pregnancy outcomes.
Choi JM, et al. Increased Prevalence of Celiac Disease in Patients with Unexplained Infertility in the United States: A Prospective Study. J Reprod Med, 2011; 56(5-6): 199–203 http://www.ncbi.nlm.nih.gov/pubmed/21682114