Scientific study: serological tests in gluten sensitivity
- Blood samples were collected from 78 patients with gluten sensitivity and 80 patients with celiac disease and were tested for a variety of immune and antibody markers.
- Results suggested certain key markers known to be associated with celiac disease are not found in patients with gluten sensitivity.
- Other immune markers were noted in some patients with gluten sensitivity, but not in proportions of patients large enough to be considered both sensitive and specific.
Further research is needed to establish definitive markers for gluten sensitivity. Absence of known markers for celiac disease can assist in diagnosis of gluten sensitivity, along with presence of clinical symptoms that may include both intestinal and extra-intestinal symptoms.
Volta U, et al. Serological tests in gluten sensitivity (nonceliac gluten intolerance). J Clin Gastroenterol, 2012; 46(8):680-685.